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November 30, 2021

Kalion completes first, full-scale glucaric acid production

Industrial biotech company presents update and additional growth plan at leading industry conference 

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October 12, 2021

Building a better chemical factory—out of microbes

Metabolic engineers have a problem: cells are selfish. The scientists want to use microbes to produce chemical compounds for industrial applications. The microbes prefer to concentrate on their own growth. 

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October 27, 2020

Kalion Inc. Teams with Agile BioFoundry To Win DOE Grant to Advance Bio-based Glucaric Acid

Kalion Inc. (pronounced KAL-LEE-ON), along with 8 other companies, was selected by the U.S. Department of Energy to receive $5.7 million in funding with the Agile BioFoundry consortium ( to advance the fundamental understanding of industrial biotechnology. Kalion Inc. uses machine learning to accelerate the development of high-purity, low-cost glucaric acid. Glucaric acid and its related compounds enhance sustainability as well as improve the chemical properties of products and applications ranging from water treatment, polymers & textiles, coatings, detergents, and pharmaceuticals.

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August 13, 2020

Kalion Inc. Receives NSF Phase II SBIR Grant to Develop Bio-based Glucaric Acid

Milton, Massachusetts, July 30, 2020 – Kalion Inc. (pronounced KAL-LEE-ON) has been awarded a National Science Foundation (NSF) Phase II Small Business Research (SBIR) grant for $746,822 to conduct research and development work improving the bio-based production of glucaric acid. Glucaric acid and its related compounds enhance sustainability as well as improve the chemical properties of products ranging from water treatment, polymers & textiles, coatings, detergents and pharmaceuticals.

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January 6, 2020

Catalyzing Commercialization: High-Purity Glucaric Acid Produced by Microbes

The American Institute of Chemical Engineers published this article about Kalion, Inc. in December 2019. 

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June 10, 2019

EPA Honors Winners of the 2019 Green Chemistry Challenge Awards

Innovative technologies decrease hazardous chemicals, reduce costs, and spur economic growth

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July 24, 2018

Researchers investigate new biobased fibers

This article first appeared on Plastics News.

A research team at North Carolina State University says biobased glucaric-acid or lignin additives can dramatically increase the toughness of polyvinyl alcohol fibers.

As a new anti-plasticizer, the additive can nearly triple the resin's tensile strength and double its modulus, and the enhanced PVA fibers can find uses in biofriendly products such as fibers and polymers, detergents, paints and diapers.

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February 21, 2018

Antiplasticizing Behaviors of Glucarate and Lignin Bio‐Based Derivatives on the Properties of Gel‐Spun Poly(Vinyl Alcohol) Fibers


Petrol and biochemical plasticizers are added to poly(vinyl alcohol) (PVA) to improve its processability while tuning its moisture sensitivity. But those additives often reduce the mechanical performance of PVA products. In this study, the antiplasticization and properties of PVA containing additives from biorenewable sources are studied.

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July 14, 2017

5 minutes with… Darcy Prather, President of Kalion.

"One of the greatest challenges dealing with technology this early in the supply chain is that it often requires you to re-think how you might operate throughout the value chain."

Our world demands more materials and polymers to respect the environment and transfer the billions spent on our oil based industries to renewable sources. The challenge arises when striking the balance between these desires and the practicalities of paying more for renewable substitutes. This means that more chemical companies are refining their production processes and the strategies they use to become more competitive on price.

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April 21, 2017

Four Small Businesses to Collaborate with Berkeley Lab Through Small Business Vouchers

The U.S. Department of Energy (DOE) announced that 38 small businesses will collaborate with national lab researchers through the Small Business Vouchers (SBV) pilot, including four that will work with Lawrence Berkeley National Lab (Berkeley Lab) in the areas of bioenergy and advanced manufacturing.

The innovative SBV pilot facilitates access to the DOE national labs for U.S. small businesses, enabling them to tap into the intellectual and technical resources they need to overcome critical technology challenges for their advanced energy products and gain a global competitive advantage.

Eight DOE national laboratories will receive funding to partner with 38 competitively selected small businesses across the country.

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